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An interesting paper by OActive Project partner CERTH about the “Physical Activity as a Risk Factor in the Progression of Osteoarthritis: A Machine Learning Perspective” is now published in the conference proceedings of the “International Conference on Learning and Intelligent Optimization LION 2020: Learning and Intelligent Optimization”.

Abstract

“Knee osteoarthritis (KOA) comes with a variety of symptoms’ intensity, frequency and pattern. Most of the current methods in KOA diagnosis are very expensive commonly measuring changes in joint morphology and function. So, it is very important to diagnose KOA early, which can be achieved with early identification of significant risk factors in clinical data. Our objective in this paper is to investigate the predictive capacity of physical activity measures as risk factors in the progression of KOA. In order to achieve this, a machine learning approach is proposed here for KOA prediction using features extracted from an accelerometer bracelet. Various ML models were explored for their suitability in implementing the learning task on different combinations of feature subsets. Results up to 74.5% were achieved indicating that physical activity measured by accelerometers may constitute an important risk factor for KOA progression prediction especially if it is combined with complementary data sources”.

For more information click here

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The OActive project is organising a training seminar aiming to “Engage end users to the OActive world“, which will be held ONLINE on 29th of May.

The training session will bring together EU and national representatives from:
– the medical care industry
– General public (Individuals, OA patients, elderly, athletes),
– Regulatory authorities (Ministries of health, organisations, orthopaedic associations, etc.)
– Research & education communities

OActive targets patient specific prediction and interventions by using a combination of biomarkers, behavioural modelling, mechanistic computational models, simulations and big data analytics. Scientists from well-established institutes around Europe (including University of Nicosia, LEITAT, KULeuven, Smartex, Liverpool John Moores University, CERTH, University of Patras, RIMED) will give lectures during the training. Participants will be able to raise questions to the panel of experts.

To attend the training please follow the above link to register until 28th of May 2020.

For registration visit here

Participants will be able to attend the meeting for FREE. The training will be organized via an online platform, which will be provided upon registration.

For more information take a look at the agenda: 

 

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Our Partner Ri.MED has just got a paper out in the journal Biofabrication (IF 7.236)
I. Chiesa, C. De Maria, A. Lapomarda, G.M. Fortunato, F. Montemurro, R. Di Gesù, R.S. Tuan, G. Vozzi, R. Gottardi. “Endothelial cells support osteogenesis in an in vitro vascularized bone model developed by 3D bioprinting.” Biofabrication. Published online ahead of printing. Visit link: https://iopscience.iop.org/article/10.1088/1758-5090/ab6a1d

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The OActive project 24M meeting took place in Palermo on 25th of November 2019 hosted by Ri.MED. All partners presented the work performed and their future plans. Ri.MED offered a guided tour of the consortium in its premises.

On 26th of November a training session was organised by AXIA Innovation with the support of Project Coordinator from University of Nicosia and Ri.MED. A training session was organised in order to ensure the best understanding and the efficient transfer of knowledge among RTD and computational partners. The ultimate goal was to bridge the two different worlds giving an opportunity of communication.


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Oactive´s partner RI.MED Foundation participated from the 20th-22nd of October 2019 in the International Conference on Biofabrication in Columbus, Ohio, USA.

Biofabrication 2019 brought together scientists, engineers, regulatory specialists, industry participants, and clinical investigators from around the world to present and share their recent discoveries, research direction, and views on the current problems and opportunities in the exciting field of biofabrication. Five plenary, sixteen keynote, ninety podium, and hundreds of poster presenters gathered for two and a half days at The Ohio State University in Columbus, Ohio. 

In addition to a sponsor’s trade show, special fora were held on publishing strategies, transnational research, regulatory issues, industrial technologies, and opportunities for young researchers.

For more information visit:

https://www.biofabrication2019.org

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To coincide with National Biomechanics Day on 10 April 2019 – a worldwide celebration of all things Biomechanics, The University of Huddersfield hosted a very successful Biomechanics Interest Group event themed ‘Applied Biomechanics – the application to real life’. The ever popular event had over 120 registered delegates from across the country and saw a range of stimulating and informative talks from students, lecturers and Professors.
On behalf of our partner Liverpool John Moores University, Bill Baltzopoulos presented the keynote examining the latest technology he and his team are employing, studying ‘Biomechanics of the musculoskeletal system in-vivo and implications for muscle and joint forces in different applied conditions’. The presentation focused on the work of our group on musculoskeletal biomechanics, including an update of the progress of the musculoskeletal modelling tools in the OACTIVE project.

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Our partner University of Patras participated at the event “Patras Innovation Quest (Patras IQ)a Technology Transfer Exhibition” which was held on the 12th -14th of April 2019 in Patras, Greece.

The main objective of Patras IQ is to create a critical competitive advantage both in the research community as well as in the productive sector, through a constant effort to solve problems and apply innovative ideas for the development of new products and services and the optimization of existing ones, which aspire to conquer a part of the national and global market.

Patras IQ has been honored as the National winner and representative for the European Enterprise Promotion Awards (EEPA 2017), and has received the Education Business Award of 2016, and has been established as the continuous meeting of interconnection of know-how & innovation with entrepreneurship.

The exhibitoin is co-organized by University of Patras, the Ministry of Education, Research & Religious Affairs, the Ministry of Economy & Development, the Chamber of Achaia, the Region of Western Greece, the Hellenic Open University and the Technological Educational Institute of Western Greece.

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The Visualization and Virtual Reality Group has been selected by the European Commission as a finalist in the category “Tech of Society” for the Innovation Radar Prize 2019. The Innovation Radar is among others a “scouting” activity of the EC and aims to identify innovative research of single organizations in the context of European projects. Initially 40 finalists were selected spread in four categories. After online voting of the public the VVR group has been ranked 2nd in the Tech for Society category.  https://ec.europa.eu/futurium/en/innovation-radar-prize/tech-for-society-2019

Within the OActive project, University of Patras is interested in predicting the severity of osteoarthritis and then derive a personalized intervention strategy to delay the progression of the disease. To achieve this, they rely on automatic methods for creating multi-scale subject-specific finite element models of the knee from magnetic resonance images. These models are further constrained from experimentally measured kinematics and externally applied forces in order to simulate more complex movement behaviors like gait. Through simulation, the loading of the soft tissues is identified and is is decided how to change the habits of individuals through gait retraining and augmented reality.

There are two major outcomes related to this work. The first is related to the subject-specific modeling, simulation and analysis of the knee mechanics, which is of baseline research nature with long term goals targeting not only to osteoarthritis but planning of surgeries for anterior ligament reconstruction and knee replacement through simulation. The second is related to the development of a modular framework for extracting meaningful quantities from experimental measurements and musculoskeletal models in real-time. This can facilitate application in the broad field of rehabilitation, ergonomics, control of exoskeleton and assistive devices.

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